Table 3. Trends in Serum Total Cholesterol of US Adults, 1960-1962 to 1999-2002* Serum Total Cholesterol, mg/dL 1971-1974 1976-1980 1988-1994 1999-2002 1960-1962 P No. Mean (SE) No. Mean (SE) No. Mean (SE) No. Mean (SE) No. Mean (SE) Value All, age, y 20-74 6098 222 (1.5) 13106 216 (0.8) 11 864 215 (1.1) 13 914 204 (0.7) 7740 203 (0.9) .39 20§ 15 719 206 (0.7) 8809 203 (0.8) .009 Men, age, y 20-74 2841 220 (1.9) 4992 215 (1.1) 5604 213 (1.0) 6551 204 (0.9) 3649 203 (1.2) .51 20§ 7392 204 (0.9) 4165 202 (1.2) .19 20-29 576 189 (2.2) 986 190 (1.4) 1261 188 (1.5) 1551 180 (1.1) 674 183 (1.9) .18 30-39 698 217 (3.3) 654 210 (1.9) 871 209 (1.8) 1387 201 (1.6) 673 200 (1.5) .65 40-49 638 230 (2.5) 715 228 (2.4) 695 223 (1.6) 1168 211 (1.7) 760 212 (2.9) .77 50-59 475 231 (2.9) 717 229 (2.6) 691 229 (1.9) 825 216 (2.1) 571 215 (2.2) .74 60-74 454 232 (2.4) 1920 226 (1.9) 2086 223 (1.6) 1620 214 (1.5) 971 204 (1.6) .001 75 841 205 (1.8) 516 195 (2.8) .005 Women, age, y 20-74 3257 225 (1.6) 8114 217 (0.9) 6260 216 (1.2) 7363 205 (0.8) 4091 202 (0.8) .01 20§ 8327 207 (0.8) 4644 204 (0.7) .009 20-29 747 189 (1.8) 2283 189 (1.3) 1366 187 (1.5) 1757 183 (1.7) 961 183 (1.3) .99 30-39 764 207 (1.9) 1687 200 (1.4) 986 197 (1.3) 1749 189 (1.3) 861 194 (1.5) .02 40-49 739 224 (2.6) 1233 218 (1.8) 766 218 (1.9) 1297 204 (1.4) 754 203 (1.6) .64 50-59 529 256 (2.3) 780 241 (2.4) 793 243 (2.4) 956 228 (1.9) 569 216 (1.6) .001 60-74 478 263 (2.9) 2131 250 (1.6) 2349 247 (1.3) 1604 235 (1.6) 946 223 (1.4) .001 75 964 231 (2.3) 553 217 (1.7) .001 SI conversion: To convert serum total cholesterol to mmol/L, multiply by 0.0259. *Data are from the first National Health Examination Survey (1960-1962), the first National Health and Nutrition Examination Survey (NHANES I) (1971-1974), NHANES II (1976- 1980), NHANES III (1988-1994), and NHANES 1999-2002. Test of difference between NHANES III (1988-1994) and NHANES 1999-2002. Age-adjusted for the entire population by the direct method to the US census population projected estimates for the year 2000 using the age groups 20 to 39 years, 40 to 59 years, and 60 to 74 years.42 §Age-adjusted for the entire population by the direct method to the US census population projected estimates for the year 2000 using the age groups 20 to 39 years, 40 to 59 years, and 60 years or older.42